Thorne Research 5-MTHF

Thorne Research


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60 capsules

Thorne Research 5-MTHF is a powerhouse of vitamin B9 (also called folate or folic acid). It’s perfect for pregnant women or anyone with low vitamin B!

  • Essential for pregnancy and vitamin B deficiency*
  • Supports a bright mood and better brain health* 
  • Increases health of the heart and nervous system*

Thorne Research 5-MTHF

Struggling to keep your vitamin B levels within the normal range? Here’s a helpful solution that’s easy on your body! As many as three in five Americans have a genetic disorder that makes it difficult for their body to naturally convert folic acid into 5-MTHF. Thorne Research 5-MTHF does all of the work for you to help you overcome a vitamin B deficiency! 

What is Thorne Research 5-MTHF? It’s vitamin B9! This essential B vitamin is the active form of folate. It’s crucial for a healthy pregnancy and fetal growth, but this supplement isn’t just for expectant mothers.*

  • Pregnancy: Mamas and expectant mothers, keep you and your baby nourished during pregnancy with a folic acid supplement!* According to the CDC and the American College of Obstetricians and Gynecologists, pregnant women should take a prenatal vitamin that includes folic acid.*
  • Infants: Plenty of folic acid is key to a healthy pregnancy and baby! A maternal vitamin B deficiency can contribute to low birth weight or neural defects. Keep your baby healthy, nourished, and developmentally on track with a folic acid supplement like Thorne Research 5-MTHF!*
  • Mood: Folate plays a role in the production of melatonin (the sleep hormone), serotonin (a mood-boosting hormone), dopamine (the pleasure hormone), epinephrine (adrenaline), norepinephrine (the fight or flight hormone).*
  • Brain: Because folate helps produce essential neurotransmitters, it also protects the brain against cognitive decline.*
  • Heart: B vitamins, including folate/folic acid, participate in the metabolism of homocysteine, which may reduce your risk of cardiovascular disease or stroke.* 
  • Nerves: Support healthy nerves with a folate supplement like Thorne Research 5-MTHF! In particular, a regular vitamin B supplement may encourage healthier nerve tissues and repair.*

Thorne Research 5-MTHF is recommended for pregnant women, especially during the first trimester, but is also perfect for any individual with low vitamin B levels. Want to make sure this is the best vitamin B supplement for you? Our certified Wellness Consultants are here to provide you with personalized support and supplement recommendations to suit you and your family! Get in touch!

Suggested Use:

  • 1 mg: Take 1 capsule one to three times daily or as recommended by your health professional.
  • 5 mg: Take 1 capsule one to two times daily or as recommended by your health professional.

Cautions: Keep out of the reach of children. Consult a physician before taking this product if you are pregnant, nursing, taking any medications, or have a medical condition. 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate’s anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

Allergy Warning: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Questions? We’ve got answers! Reach out to our support team for help.

Serving Size: 1 Capsule

Servings Per Container: 60

Ingredients: Folate (as L-5-Methyltetrahydrofolate†)

Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide

Thorne Research is a group of experts in the field of human health. Their mission is to redefine what it means to be well and to push the limits of human potential. In their opinion, good health can always be made better — no one should be limited by a definition of health that’s less than excellent.

And how do you find out what your state of health is? Finding out what your body needs is only half the solution. Supplying nutrients to support your needs is the other half.

Thorne Research has developed personal at-home test kids to help people understand true health and the supplements that will help you unlock it.

Thorne has invested endless time and effort into their research and they have partnered with 12 USA Teams and Pro Athletes as well as Mayo Clinic. Their innovation labs and clinical research fuels every product they create. Every product is created with strict quality standards and even more testing.

At The Healthy Place, we strive for accuracy in our product images and information. However, manufacturers may make changes to product packaging or ingredients that are not yet reflected on our site. We recommend that you read the labels, warnings, and directions on purchased products before use and not rely solely on the information provided by The Healthy Place.

The information provided here is not intended to diagnose, treat, cure, or prevent any disease. All information and recommendations given on this site, in email correspondence, newsletters or other materials provided by The Healthy Place is for informational and educational purposes only and should not be construed as medical advice nor be viewed as a substitute for a face-to-face consultation with a healthcare provider. Consult a licensed healthcare practitioner before modifying, stopping, or starting the use of any medications, health programs, diets, and/or supplements, as well as regarding any health concerns you may have. Our statements and information have not been evaluated or approved by the Food and Drug Administration. As with any health-related program, product, or service, your risks and results may vary. We expressly disclaim responsibility to any person or entity for any liability, loss, or damage caused directly or indirectly as a result of the use, application, or interpretation of the information provided to you here.