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Thorne Research

Thorne Research 5-MTHF

$24.00
Potency and Size

60 capsules

Give your body the active form of folate — one that it can use right away! Thorne 5-MTHF provides vitamin B9 in one of its most bioavailable forms to support healthy methylation, cellular energy, and overall wellness.*

  • Supports optimal folate levels and nutrient absorption*
  • Promotes healthy cellular function and energy production*
  • Encourages balanced mood and cognitive wellness*
  • Essential nutrient support for reproductive health*
  • Contains the active, ready-to-use form of folate (5-MTHF)*
View Supplement Facts

Thorne 5-MTHF Capsules


Thorne 5-MTHF delivers vitamin B9 — the active form of folate your body can readily use. This essential B vitamin supports healthy cell growth, energy metabolism, and overall wellness.*


Folate also plays a key role in methylation, a natural process that helps regulate many body functions. With its highly bioavailable form of folate, Thorne 5-MTHF provides efficient nutrient support for those who want to maintain healthy folate levels without relying on standard folic acid conversion.*



  • Provides vitamin B9 in its active methylated form*

  • Supports healthy methylation and overall nutrient utilization*

  • Aids in energy and cell function*

  • Convenient, easy-to-absorb capsule format*


Nutrient Support for Every Stage


Folate is an essential vitamin needed for new cell growth and development. Its full name is a real mouthful — 5-methyltetrahydrofolate — which is why it is often abbreviated as 5-MTHF. It’s perfect for folks who are looking to support reproductive wellness, energy levels, or general nutrient balance. Thorne 5-MTHF delivers active folate in a clean, effective formula to keep your body feeling strong and your mind clear.*



  • Promotes healthy red blood cell formation*

  • Supports reproductive and prenatal wellness*

  • Encourages a calm, balanced mood*

  • Nourishes brain and nervous system health*


Pure Ingredients, Trusted Quality


Thorne is known for its commitment to purity, potency, and transparency. Each batch of 5-MTHF undergoes rigorous testing to ensure quality and consistency. This B vitamin is free from gluten, soy, and artificial ingredients, making it a trusted choice for daily folate support.*



  • Contains the biologically active form of folate (5-MTHF)*

  • Free from gluten, soy, and artificial additives*

  • Manufactured to the highest quality standards*

  • Non-GMO and easy on digestion*


FAQs About Thorne 5-MTHF Capsules


Q: What is Thorne 5-MTHF? A: It’s vitamin B9 in its active, methylated form — an essential nutrient for healthy cell growth and function.*


Q: Who can benefit from Thorne 5-MTHF? A: Anyone looking to support healthy folate levels, energy production, or reproductive wellness can benefit from this formula.*


Q: Is this product suitable during pregnancy? A: Folate is an essential vitamin for women of childbearing age. If pregnant or nursing, consult a healthcare professional before use.*


Q: Can Thorne 5-MTHF be taken with other B-complex vitamins? A: Yes — it can complement a balanced B-vitamin routine for enhanced methylation and energy support.*


Support Your Wellness with Active Folate


Choose a folate that’s ready to go to work. Thorne 5-MTHF provides your body with a clean, active form of vitamin B9 to help maintain balanced wellness and daily vitality.*


But wait — before you go: Do you need a little helpful guidance on what your supplement routine is missing? Our Certified Wellness Consultants are always here to help you find the best natural supplements for your needs. Reach out via phone, email, or LiveChat for fast help finding whatever it is you need!*

Suggested Use:

  • 1 mg: Take 1 capsule one to three times daily or as recommended by your health professional.

  • 5 mg: Take 1 capsule one to two times daily or as recommended by your health professional.

Cautions: Keep out of the reach of children. Consult a physician before taking this product if you are pregnant, nursing, taking any medications, or have a medical condition. 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

Allergy Warning: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Questions? We’ve got answers! Reach out to our support team for help.
Serving Size: 1 Capsule

Servings Per Container: 60

Ingredients: Folate (as L-5-Methyltetrahydrofolate†)

Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide

At The Healthy Place, we strive for accuracy in our product images and information. However, manufacturers may make changes to product packaging or ingredients that are not yet reflected on our site. We recommend that you read the labels, warnings, and directions on purchased products before use and not rely solely on the information provided by The Healthy Place.

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