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Pure Encapsulations

Pure Encapsulations MethylAssist Capsules

$6400

Pickup currently unavailable at Fitchburg

90 capsules

This specialized form of methylated B vitamins gives your body support for emotional, cardiovascular, and neural well-being.*

  • Helps promote healthy methylation*
  • Supports neural and emotional health*
  • Maintains cardiovascular well-being*
  • Contains activated forms of vitamins B6, B12, and folate
  • Source of benfotiamine
View Supplement Facts

Pure Encapsulations MethylAssist


Pure Encapsulations MethylAssist supports healthy methylation*, a vital process that occurs in our bodies at the molecular level. This process helps maintain neurological, cardiovascular, immune, and emotional well-being*. MethylAssist contains methylated B vitamins, which help support methylation and a healthy nervous system*.



  • Vitamins in Activated Form: Contains vitamins B12, folate, B6, and benfotiamine


  • Body-Wide Benefits: Promotes a healthy immune response*


  • Supports Healthy Methylation: Yes


  • Promote Cardiovascular Health: Supports a healthy heart*


But what is methylation? Why does it matter? If you’re not familiar with this word, you’re not alone because most of us have never heard it, even though it’s happening all the time in our bodies.


The process of methylation is actually pretty simple. Methylation occurs when a methyl group, which is a molecule composed of three hydrogen atoms and one carbon atom, is transferred from one substance to another.


The methylation cycle helps us function physically and mentally, and this cycle plays a role in many functions throughout the body. The body’s natural detoxification process*, estrogen metabolism, fat metabolism, DNA production, hormone balance, energy production, and neurotransmitter health are just a few of the systems that rely on methylation.


B vitamins are a key part of the methylation cycle. If the body has low levels of methylated B vitamins, it won’t transfer methyl groups as efficiently, which in turn may affect an array of body functions. There are many foods that contain vitamin B, but the body must transform these into their active form to help with methylation*.


MethylAssist contains methylated folate and other active forms of vitamin B that help support the body’s natural production of key compounds involved in multiple wellness pathways*. Folks looking for a powerful supplement that contains methylated B12 and other active forms should consider Pure Encapsulations MethylAssist to help promote healthy methylation*.



Reviewed for accuracy by our licensed clinical team — doctors, nurse practitioners, and functional medicine specialists at The Healthy Place Clinic in Madison, WI.


Suggested Use: As a dietary supplement, take 1 capsule daily, with a meal, or as directed by a health professional.

Cautions: Keep out of the reach of children. Consult a physician before taking this product if you are pregnant, nursing, taking any medications, or have a medical condition.

Questions? We’ve got answers! Reach out to our support team for help.

Serving Size: 1 Capsule
Servings Per Container: 90

Ingredients:

  • Vitamins: Vitamin B6 (as pyridoxal 5' phosphate) (activated B6), Folate (as Metafolin®, L-5-MTHF), Vitamin B12 (as methylcobalamin), BenfoPure® benfotiamine

Other Ingredients: Hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water)

FAQs About Pure Encapsulations MethylAssist Capsules

Q: What are people usually taking MethylAssist for? A: Mostly for methylation support.* It uses active forms of B6, folate, and B12, so people often pick it for homocysteine metabolism support,* nerve health support,* or because they specifically want methylated B vitamins.

Q: Does this use methylfolate or regular folic acid? A: It uses methylfolate, not folic acid. You get 1,000 mcg of L-5-MTHF as Metafolin®, listed as 1,667 mcg DFE on the Supplement Facts, plus 1,000 mcg of methylcobalamin for B12.

Q: How do I take it? A: Take one capsule a day with food. Breakfast or lunch is probably best, since methylated B vitamins can feel a little stimulating for some people.

Q: Why does this one include benfotiamine? A: Benfotiamine is a fat-soluble form of vitamin B1, and this one gives you 75 mg. People usually take it for nerve support* or to help maintain healthy glucose metabolism already within the normal range,* especially alongside methylated B vitamins.

Q: I've heard methylated B vitamins can make some people feel off. Is that true? A: Yeah, sometimes. With 16 mg of activated B6, 1,000 mcg of methylfolate, and 1,000 mcg of methylcobalamin, some people might feel wired, headachy, or just kind of off. If you know you’re sensitive, take one capsule earlier in the day.

Q: Should I take this if I'm pregnant or nursing? A: I’d check with your OB or midwife before starting it. Folate matters a lot in pregnancy, but the dose here is specific, and you’d want to make sure it fits with your prenatal and anything else you’re taking.

At The Healthy Place, we strive for accuracy in our product images and information. However, manufacturers may make changes to product packaging or ingredients that are not yet reflected on our site. We recommend that you read the labels, warnings, and directions on purchased products before use and not rely solely on the information provided by The Healthy Place.

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